Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL508250 | 0.83 | MAPT (0.49) | MAPTCSNK2A1SMN1; SMN2GABRPGABRD | |
| SCHEMBL16889139 | 0.82 | RAB9A (0.42) | NPC1RAB9AMEN1MAPTMAPK1 | |
| SCHEMBL16233092 | 0.82 | PIK3CD (0.47) | MAPTCSNK2A1HRH3KEAP1NFE2L2 | |
| Hydrochloric Acid SCHEMBL5010371 | 0.81 | MAPT (0.47) | MAPTCSNK2A1GABRPGABRDGABRA1 | |
| SCHEMBL12217658 | 0.81 | HRH3 (0.37) | CSNK2A1HRH3KEAP1NFE2L2 | |
| SCHEMBL9344173 | 0.81 | MAPT (0.41) | NPC1RAB9AMEN1MAPTMAPK1 | |
| SCHEMBL9388103 | 0.79 | MAPT (0.44) | NPC1RAB9AMEN1MAPTMAPK1 | |
| SCHEMBL507380 | 0.79 | MCHR1 (0.39) | CSNK2A1HRH3KEAP1NFE2L2 | |
| SCHEMBL3334395 | 0.78 | KDM4E (0.53) | NPC1RAB9AMEN1MAPTMAPK1 | |
| SCHEMBL30325064 | 0.78 | PPARG (0.38) | MAPTCSNK2A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019148055-A9 | IMIDE-BASED MODULATORS OF PROTEOLYSIS AND METHODS OF USE | YALE UNIVERSITY (US) | 2019-09-26 | — | — | WO | disclosed |