Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195254 | 0.92 | ACACB (0.42) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL20195249 | 0.84 | MAPT (0.50) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL1843048 | 0.80 | MEN1 (0.47) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL13848403 | 0.79 | KDM4E (0.41) | MAPTCYP3A4L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL21391268 | 0.79 | NPC1 (0.45) | MAPTMEN1KMT2ACYP3A4KDM4E | |
| SCHEMBL16889139 | 0.79 | RAB9A (0.42) | MAPTMEN1KMT2ACYP3A4L3MBTL1 | |
| SCHEMBL3229511 | 0.79 | NNMT (0.44) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL9344173 | 0.78 | MAPT (0.41) | MAPTMEN1KMT2ACYP3A4L3MBTL1 | |
| SCHEMBL19405295 | 0.78 | APP (0.40) | MAPTMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL300799 | 0.77 | PIK3CD (0.43) | MAPTKMT2AALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1083811-A | The pyridine oxyethyl group of quinoline and quinazoline, pyridine ethylamino and pyridine propyl derivatives | DOWELANCO (US) | 1994-03-16 | — | — | CN | disclosed |
| WO-1994004527-A1 | PYRIDYLETHOXY-, PYRIDYLETHYLAMINO-, AND PYRIDYLPROPYL-DERIVATIVES OF QUINOLINE AND QUINAZOLINE AS INSECTICIDES AND FUNGICIDES | DOWELANCO (US) | 1994-03-03 | — | — | WO | disclosed |