Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9360618 | 0.88 | ACACB (0.40) | MAPTCYP3A4CYP2D6HRH3GABRP | |
| SCHEMBL10433961 | 0.82 | MAPT (0.39) | MAPTMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL1843048 | 0.81 | MEN1 (0.47) | MAPTMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL21391268 | 0.81 | NPC1 (0.45) | MAPTMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL16889139 | 0.81 | RAB9A (0.42) | MAPTMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL647523 | 0.79 | L3MBTL1 (0.49) | MAPK1CYP3A4L3MBTL1LTA4HNR5A1 | |
| SCHEMBL9345370 | 0.78 | MAPT (0.49) | MAPTRAB9AGABRPGABRDGABRA1 | |
| SCHEMBL9388103 | 0.78 | MAPT (0.44) | MAPTMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL25592544 | 0.77 | LTA4H (0.52) | MAPTMEN1RAB9AKMT2ANPC1 | |
| SCHEMBL5530443 | 0.75 | RAB9A (0.53) | MAPTMEN1RAB9AKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393453-B1 | Process for the preparation of 2-chloro-5-chloromethyl-pyridine and new intermediates | BAYER AG (DE) | 1994-11-30 | — | — | EP | disclosed |
| US-5329011-A | Process for the preparation of 2-chloro-5-chloromethyl-pyridine, and new intermediates | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| EP-0393453-A2 | Process for the preparation of 2-chloro-5-chloromethyl-pyridine and new intermediates | BAYER AG (DE) | 1990-10-24 | — | — | EP | disclosed |