Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.66 |
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.66 |
| ▸ | HPGD | P15428 | 5/20 | 0.66 |
| ▸ | CASP3 | P42574 | 2/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.60 |
| ▸ | PTPN5 | P54829 | 6/20 | 0.60 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.60 |
| ▸ | UTRN | P46939 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30943188 | 1.00 | RAB9A (0.66) | RAB9ANPC1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL28028562 | 0.86 | SMN1; SMN2 (0.57) | RAB9ANPC1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL13528498 | 0.84 | NPC1 (0.72) | RAB9ANPC1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL24454868 | 0.83 | RAB9A (0.76) | RAB9ANPC1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL30486931 | 0.83 | RAB9A (0.76) | RAB9ANPC1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL6681353 | 0.83 | NPC1 (0.70) | RAB9ANPC1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL7905531 | 0.82 | SMN1; SMN2 (0.70) | RAB9ANPC1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL2244575 | 0.82 | SMN1; SMN2 (0.70) | RAB9ANPC1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL13254495 | 0.82 | KDM4E (0.59) | RAB9ANPC1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL9018554 | 0.81 | NPC1 (0.68) | RAB9ANPC1KDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232658-B | Chiral rhodium complex and preparation and application thereof | 中国科学院福建物质结构研究所 | 2020-10-27 | — | — | CN | claimed |
| CN-115739190-B | Metal complex catalyst for phytic acid and preparation method and application thereof | 江南大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-115739190-A | Phytic acid metal complex catalyst and preparation method and application thereof | 江南大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-112654608-A | Condensed ring compounds having urea structure | 桑福德伯纳姆普利斯医学发现研究所 | 2021-04-13 | — | — | CN | disclosed |
| CN-109232658-B | Chiral rhodium complex and preparation and application thereof | 中国科学院福建物质结构研究所 | 2020-10-27 | — | — | CN | disclosed |
| US-8242278-B2 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-08-14 | — | — | US | disclosed |
| US-20120101278-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | HAGIYA KOJI (JP) | 2012-04-26 | — | — | US | disclosed |
| EP-1473286-B1 | PROCESS FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-20090216017-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | HAGIYA KOJI | 2009-08-27 | — | — | US | disclosed |
| US-7554000-B2 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-30 | — | — | US | disclosed |
| US-20050096471-A1 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-05-05 | — | — | US | disclosed |
| EP-1473286-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2004-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101278-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | PPOX, CAT, TYR | RAB9A 2254/4885NPC1 4102/4885KDM4E 3428/4885 |
| US-20090216017-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | PPOX, CAT, TYR | RAB9A 2254/4885NPC1 4102/4885KDM4E 3428/4885 |
| US-20050096471-A1 | Process for producing biaryl compound | PPOX, CAT, TYR | RAB9A 2254/4885NPC1 4102/4885KDM4E 3428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.