SCHEMBL21391593

SCHEMBL21391593

Cc1cc(-c2ccc3c(c2)C(C)c2cc(Br)ccc2-3)c(C)cc1Br

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20233481 1.00 PGR (0.42) PGR
SCHEMBL20233477 0.79 PGR (0.46) PGR
SCHEMBL2146997 0.78 PGR (0.53) PGR
SCHEMBL4818132 0.74 S100A4 (0.52)
SCHEMBL13718931 0.70 PGR (0.47) PGR
SCHEMBL17882478 0.69 PGR (0.43) PGR
SCHEMBL13779987 0.68 ALDH1A1 (0.46)
SCHEMBL17277083 0.68 BCHE (0.39)
SCHEMBL13995259 0.66 PGR (0.41) PGR
SCHEMBL30626124 0.66 AHR (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190296242-A1 POLYMERS WITH ASYMMETRIC REPEATING UNITS MERCK PATENT GMBH (DE) 2019-09-26 US disclosed