Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14394443 | 0.80 | DAO (0.47) | DAOTRPA1CYP1A2CYP2A6TP53 | |
| SCHEMBL793554 | 0.77 | GPR3 (0.46) | CYP1A2CYP2A6MAOATDP1LMNA | |
| SCHEMBL21391622 | 0.76 | MAPT (0.44) | DAOCYP1A2TP53TDP1LMNA | |
| SCHEMBL19820294 | 0.75 | ALDH1A1 (0.39) | DAOTRPA1CYP1A2CYP2A6TP53 | |
| SCHEMBL18799899 | 0.75 | CYP1A2 (0.38) | DAOTRPA1CYP1A2CYP2A6TP53 | |
| SCHEMBL11992360 | 0.73 | BCHE (0.45) | CYP1A2CYP2A6TDP1LMNAALDH1A1 | |
| SCHEMBL17265899 | 0.72 | ALDH1A1 (0.42) | MAOBCA2LMNAALDH1A1HSD17B10 | |
| SCHEMBL19073273 | 0.72 | ALDH1A1 (0.43) | CYP1A2TDP1LMNAALDH1A1HSD17B10 | |
| SCHEMBL9973674 | 0.71 | HTT (0.44) | CYP1A2TDP1LMNAALDH1A1KDM4E | |
| SCHEMBL19373835 | 0.71 | CYP1A2 (0.35) | DAOTRPA1CYP1A2CYP2A6TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119590-A1 | POLYMERS WITH AMINE-GROUP-CONTAINING REPEATING UNITS | MERCK PATENT GMBH (DE) | 2022-04-21 | — | — | US | disclosed |
| US-20210277176-A1 | FORMULATION CONTAINING A HIGHLY BRANCHED POLYMER, HIGHLY BRANCHED POLYMER AND ELECTRO-OPTICAL DEVICE CONTAINING THIS HIGHLY BRANCHED POLYMER | MERCK PATENT GMBH (DE) | 2021-09-09 | — | — | US | disclosed |
| US-20190296242-A1 | POLYMERS WITH ASYMMETRIC REPEATING UNITS | MERCK PATENT GMBH (DE) | 2019-09-26 | — | — | US | disclosed |