SCHEMBL21391889

SCHEMBL21391889

Cc1ccc(N(c2cccc(C(C)(C)C)c2)c2cccc(C(C)(C)C)c2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
HDAC8 Q9BY41 4/20 0.40
HDAC4 P56524 1/20 0.38
HDAC2 Q92769 1/20 0.38
KIF11 P52732 1/20 0.37
ALDH1A1 P00352 3/20 0.35
ACHE P22303 3/20 0.35
CYP2D6 P10635 2/20 0.35
NFE2L2 Q16236 1/20 0.34
HDAC3 O15379 1/20 0.34
HDAC11 Q96DB2 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
MAPT P10636 3/20 0.33
HCRTR2 O43614 1/20 0.33
RXRA P19793 1/20 0.33
RXRB P28702 1/20 0.33
PTAFR P25105 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20059363 0.96 TSHR (0.52) TSHRHDAC8HDAC4HDAC2KIF11
SCHEMBL18799200 0.92 TSHR (0.38) TSHRHDAC8HDAC4HDAC2KIF11
SCHEMBL12000721 0.90 KIF11 (0.47) TSHRHDAC8HDAC4HDAC2KIF11
SCHEMBL20059987 0.88 KIF11 (0.36) TSHRHDAC8HDAC4HDAC2KIF11
SCHEMBL12774505 0.86 CYP2D6 (0.45) HDAC8HDAC4HDAC2KIF11ALDH1A1
SCHEMBL27110986 0.86 CYP2D6 (0.45) HDAC8HDAC4HDAC2KIF11ALDH1A1
SCHEMBL15165369 0.84 ESR1 (0.49) TSHRHDAC8HDAC4HDAC2KIF11
SCHEMBL12000709 0.84 KIF11 (0.53) TSHRHDAC8HDAC4HDAC2KIF11
SCHEMBL19389278 0.84 HSD17B1 (0.38) TSHRHDAC8ALDH1A1MAPTNPC1
SCHEMBL2928411 0.84 RXRA (0.46) HDAC8HDAC4HDAC2KIF11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11094474-B2 Photoelectric conversion element, dye-sensitized solar cell, metal complex dye, dye composition, and oxide semiconductor electrode FUJIFILM CORPORATION (JP) 2021-08-17 US disclosed
US-20190295779-A1 PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE COMPOSITION, AND OXIDE SEMICONDUCTOR ELECTRODE FUJIFILM CORPORATION (JP) 2019-09-26 US disclosed