Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21392168 | 0.79 | APLNR (0.33) | CLK4LMNAMAPTALDH1A1MEN1 | |
| SCHEMBL21385329 | 0.75 | APLNR (0.39) | LMNAMAPTALDH1A1MEN1CYP1A2 | |
| SCHEMBL21392051 | 0.73 | CACNA1B (0.36) | LMNAALDH1A1TSHRKCNH2SMN1; SMN2 | |
| SCHEMBL21392159 | 0.73 | SLC2A1 (0.32) | LMNAALDH1A1TSHRKCNH2SMN1; SMN2 | |
| SCHEMBL25249374 | 0.71 | IGF1R (0.42) | LMNAMAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL29593822 | 0.71 | IGF1R (0.42) | LMNAMAPTMEN1CYP1A2CYP3A4 | |
| SCHEMBL29593834 | 0.70 | PDE2A (0.38) | LMNAMAPTALDH1A1MEN1CYP1A2 | |
| SCHEMBL25244541 | 0.70 | PDE2A (0.38) | LMNAMAPTALDH1A1MEN1CYP1A2 | |
| SCHEMBL21392148 | 0.70 | LMNA (0.33) | LMNAMAPTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL25282330 | 0.70 | KMT2A (0.34) | CLK4MEN1KMT2AKCNH2CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180244-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2019-09-26 | — | — | WO | disclosed |
| WO-2019179652-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2019-09-26 | — | — | WO | disclosed |