SCHEMBL21391991

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24380053	0.92	RXFP1 (0.51)	LMNAPOLBRXFP1SMN1; SMN2PTPRC
	SCHEMBL21391963	0.85	RXFP1 (0.46)	LMNAPOLBRXFP1SMN1; SMN2PTGS1
	SCHEMBL7081238	0.83	RXFP1 (0.57)	LMNAPOLBRXFP1SMN1; SMN2PTPRC
	SCHEMBL21081939	0.82	RXFP1 (0.47)	LMNAPOLBRXFP1RORC
	SCHEMBL3424865	0.82	POLB (0.76)	LMNAPOLBRXFP1SMN1; SMN2HTT
	SCHEMBL19899690	0.80	RXFP1 (0.46)	LMNAPOLBRXFP1RORCALDH1A1
	SCHEMBL20577777	0.80	RXFP1 (0.53)	RXFP1RORC
	SCHEMBL29448788	0.78	RXFP1 (0.53)	LMNAPOLBRXFP1PTPRCKCNK3
	SCHEMBL24425915	0.77	CA12 (0.47)	LMNAPOLBRXFP1RORCALDH1A1
	SCHEMBL15052244	0.77	CFTR (0.64)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.