Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanidine SCHEMBL11252247 | 1.00 | CA5A (0.61) | — | |
| Guanidine SCHEMBL1013287 | 1.00 | CA5A (0.61) | — | |
| Guanidine SCHEMBL27574673 | 1.00 | CA5A (0.61) | — | |
| Guanidine SCHEMBL742686 | 1.00 | CA5A (0.61) | — | |
| Guanidine SCHEMBL17844261 | 1.00 | CA5A (0.61) | — | |
| Guanidine SCHEMBL6384671 | 1.00 | CA5A (0.61) | — | |
| Guanidine SCHEMBL8852023 | 1.00 | CA5A (0.61) | — | |
| Guanidine SCHEMBL4613000 | 0.96 | — | — | |
| Guanidine SCHEMBL28603290 | 0.96 | CA5A (0.57) | — | |
| Guanidine SCHEMBL27704650 | 0.96 | CA5A (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8187 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122071736-A | Free DNA extraction kit, extraction method and application | 武汉华大智造科技有限公司 | 2026-05-22 | — | — | CN | claimed |
| CN-115679430-B | Titanium-aluminum composite part film removing treatment agent and titanium-aluminum composite part surface micropore treatment method | 东莞市慧泽凌化工科技有限公司 | 2026-05-19 | — | — | CN | claimed |
| US-20260131754-A1 | GAS-GENERATING AGENT COMPOSITION, GAS-GENERATING AGENT, AND PREPARATION METHOD AND USE | HUBEI HANGPENG CHEMICAL POWER TECH CO LTD (CN) | 2026-05-14 | — | — | US | claimed |
| CN-122017076-A | Method for detecting carbomer content in pharmaceutical preparation | 浙江康恩贝制药股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-12617724-B2 | Hydraulic binder composition comprising blast furnace slag | STARCIN HOLDING FRANCE (FR) | 2026-05-05 | — | — | US | claimed |
| EP-4106071-B1 | ELECTROLYTE FOR LITHIUM-SULFUR SECONDARY BATTERY AND LITHIUM-SULFUR SECONDARY BATTERY COMPRISING SAME | LG ENERGY SOLUTION LTD (KR) | 2026-04-29 | — | — | EP | claimed |
| EP-3882229-B1 | POURABLE EXPLOSIVE ACTIVE SUBSTANCE | DIEHL DEFENCE GMBH & CO KG (DE) | 2026-04-22 | — | — | EP | claimed |
| US-12606501-B2 | Ignition powder, preparation method therefor and use thereof, and airbag gas generator | HUBEI HANGPENG CHEMICAL POWER TECHNOLOGY CO., LTD. (CN) | 2026-04-21 | — | — | US | claimed |
| EP-4234642-B1 | AQUEOUS TEXTURED PAINT COATING COMPOSITION, PAINT COATING FROM THE AQUEOUS TEXTURED PAINT COATING COMPOSITION, METAL SUBSTRATE COMPRISING THE PAINT COATING, USE OF THE AQUEOUS TEXTURED PAINT COATING COMPOSITION AND METHOD FOR COATING A METAL SUBSTRATE WITH THE AQUEOUS TEXTURED PAINT COATING COMPOSITION | DAW SE (DE) | 2026-04-15 | — | — | EP | claimed |
| US-12594224-B2 | Oral care compositions and methods of use | COLGATE-PALMOLIVE COMPANY (US) | 2026-04-07 | — | — | US | claimed |
| US-4135956-A | OXIDIZER AND DECAHYDRODECABORATE SALTS | TELEDYNE MCCORMICK SELPH (US) | 1979-01-23 | — | — | US | claimed |
| US-4111728-A | POLYETHER OF POLYESTER BINDER, MAGNESIUM OXIDE OR NITRATE COATED AMMONIUM NITRATE | RAMNARACE JAWAHARLAL | 1978-09-05 | — | — | US | claimed |
| US-4094712-A | PROPELLANTS, DECAHYDRODECABORATES | TELEDYNE MCCORMICK SELPH, AN OPERATING DIVISION OF TELEDYNE INDUSTRIES, INC. (US) | 1978-06-13 | — | — | US | claimed |
| US-4089716-A | DECAHYDRODECABORATE SALTS | TELEDYNE MCCORMICK-SELPH, AN OPERATING DIVISION OF TELEDYNE INDUSTRIES, INC. (US) | 1978-05-16 | — | — | US | claimed |
| US-4080902-A | LINEARLY ENCAPSULATED EXPLOSIVE WITH METAL CLADDED PYROTECHNIC MATERIAL AROUND ENCAPSULATION | TELEDYNE MCCORMICK SELPH (US) | 1978-03-28 | — | — | US | claimed |
| US-4021382-A | Method for the preparation of hydrophilic spongy gels | CESKOSLOVENSKA AKADEMIE VED (CS) | 1977-05-03 | — | — | US | claimed |
| US-3988277-A | Stabilized Mannich base solutions | AMERICAN CYANAMID COMPANY (US) | 1976-10-26 | — | — | US | claimed |
| US-3956040-A | Explosive slurry composition containing sodium montmorillonite | GELAN KABUSHIKI KAISHA (JA) | 1976-05-11 | — | — | US | claimed |
| US-3950421-A | Method of producing triaminoguanidine nitrate | ROCKWELL INTERNATIONAL CORPORATION (US) | 1976-04-13 | — | — | US | claimed |
| US-3943954-A | Pipeline transportation of viscous hydrocarbons | TEXACO INC. (US) | 1976-03-16 | — | — | US | claimed |