Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11755028 | 0.84 | LMNA (0.36) | ALDH1A1LMNAKDM4ETYMP | |
| SCHEMBL8069779 | 0.84 | LMNA (0.36) | ALDH1A1LMNAKDM4ETYMP | |
| SCHEMBL1148704 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL27915216 | 0.79 | LMNA (0.36) | ALDH1A1LMNATYMP | |
| SCHEMBL16015602 | 0.77 | ALDH1A1 (0.35) | ALDH1A1LMNATYMP | |
| SCHEMBL1583091 | 0.77 | KDM4E (0.52) | LMNAKDM4E | |
| SCHEMBL11524208 | 0.77 | LMNA (0.31) | ALDH1A1LMNA | |
| SCHEMBL27735943 | 0.76 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL23471378 | 0.75 | — | — | |
| SCHEMBL24292513 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190291045-A1 | 1-Amino-2-Methyl-2-Propanol Derivatives | TPAT IP LLC | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190291045-A1 | 1-Amino-2-Methyl-2-Propanol Derivatives | PNMT, PKD1, PKD2 | ALDH1A1 2340/4885LMNA 1724/4885KDM4E 1153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.