Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26328524 | 0.87 | MTNR1A (0.55) | HTR2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL21392065 | 0.83 | HTR2A (0.58) | HTR2AMEN1KMT2AMAPTHTR1A | |
| SCHEMBL1460676 | 0.83 | KMT2A (0.61) | HTR2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL31370348 | 0.83 | KMT2A (0.61) | HTR2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL18029114 | 0.83 | KMT2A (0.61) | HTR2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL1460679 | 0.83 | KMT2A (0.61) | HTR2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL21392223 | 0.82 | GPR84 (0.51) | HTR2AMEN1KMT2AMAPTHTR1A | |
| SCHEMBL24328257 | 0.82 | MEN1 (0.58) | HTR2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL28413745 | 0.82 | SMN1; SMN2 (0.60) | HTR2AMEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL24328915 | 0.82 | SMN1; SMN2 (0.60) | HTR2AMEN1KMT2AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078467-B2 | Highly active self-sufficient nitration biocatalysts | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-08-03 | — | — | US | disclosed |
| US-20190292527-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078467-B2 | Highly active self-sufficient nitration biocatalysts | POR, CYP4F3, CBR3 | HTR2A 4016/4885MEN1 4390/4885KMT2A 3004/4885 |
| US-20190292527-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | POR, CYP4F3, CBR3 | HTR2A 4016/4885MEN1 4390/4885KMT2A 3004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.