Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | MPO | P05164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19872653 | 0.81 | GPR17 (0.44) | SMN1; SMN2HRH3ALDH1A1MAPTKDM4E | |
| SCHEMBL19871228 | 0.81 | MAPT (0.51) | HRH3MPOALDH1A1MAPTKDM4E | |
| SCHEMBL18028976 | 0.81 | MAPT (0.51) | HRH3MPOALDH1A1MAPTKDM4E | |
| SCHEMBL23226261 | 0.77 | HRH3 (0.40) | SMN1; SMN2HRH3MPOALDH1A1MAPT | |
| SCHEMBL20119872 | 0.77 | EGFR (0.46) | SMN1; SMN2MAPTKDM4EHSD17B10USP2 | |
| SCHEMBL20119984 | 0.75 | NPC1 (0.41) | SMN1; SMN2ALDH1A1MAPTKDM4EHSD17B10 | |
| SCHEMBL15322279 | 0.75 | HTT (0.57) | SMN1; SMN2HTTS1PR1MPOALDH1A1 | |
| SCHEMBL19872652 | 0.75 | ALDH1A1 (0.51) | SMN1; SMN2HRH3ALDH1A1MAPTKDM4E | |
| SCHEMBL21396197 | 0.74 | HRH3 (0.39) | HRH3ALDH1A1MAPTHPGDUSP2 | |
| SCHEMBL20935019 | 0.74 | HPGD (0.56) | SMN1; SMN2ALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078467-B2 | Highly active self-sufficient nitration biocatalysts | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-08-03 | — | — | US | disclosed |
| US-20190292527-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078467-B2 | Highly active self-sufficient nitration biocatalysts | POR, CYP4F3, CBR3 | SMN1; SMN2 4392/4885HTT 3686/4885HRH3 3672/4885 |
| US-20190292527-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | POR, CYP4F3, CBR3 | SMN1; SMN2 4392/4885HTT 3686/4885HRH3 3672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.