Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20120037 | 0.82 | GPR17 (0.41) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL18029272 | 0.81 | TPH1 (0.42) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL20120059 | 0.77 | MAPT (0.41) | EGFRMAPTMEN1KMT2ANPC1 | |
| SCHEMBL21392227 | 0.77 | SMN1; SMN2 (0.45) | MAPTKDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL29312428 | 0.76 | KCNQ2 (0.39) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL20120113 | 0.76 | KDM4E (0.73) | EGFRMAPTKDM4EMEN1GAA | |
| SCHEMBL21392032 | 0.76 | KLK6 (0.47) | EGFRMAPTKDM4EMEN1KMT2A | |
| SCHEMBL21392230 | 0.75 | KIF11 (0.50) | EGFRMAPTKDM4EMEN1GAA | |
| SCHEMBL19872722 | 0.75 | EGFR (0.56) | EGFRMAPTKDM4EMEN1GAA | |
| SCHEMBL18509957 | 0.75 | FBP1 (0.48) | MAPTKDM4EFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018081456-A1 | HIGHLY ACTIVE SELF-SUFFICIENT NITRATION BIOCATALYSTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-05-03 | — | — | WO | disclosed |