SCHEMBL21392268

SCHEMBL21392268

CC(C)(C)c1ccc(N2c3ccccc3Oc3cc(B4OC(C)(C)C(C)(C)O4)ccc32)cc1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.37
LPL P06858 7/20 0.37
LIPG Q9Y5X9 7/20 0.37
ROCK1 Q13464 1/20 0.31
IRAK4 Q9NWZ3 1/20 0.31
PRMT5 O14744 1/20 0.30
WDR77 Q9BQA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13833029 0.88 LIPG (0.45) LPLLIPGROCK1IRAK4PRMT5
SCHEMBL3475430 0.87 P2RX4 (0.40) HIF1ALPLLIPGROCK1IRAK4
SCHEMBL20114066 0.86 LIPG (0.55) LPLLIPGROCK1IRAK4
SCHEMBL12620488 0.84 LIPG (0.40) HIF1ALPLLIPG
SCHEMBL18544780 0.84 LIPG (0.49) LPLLIPGROCK1IRAK4PRMT5
SCHEMBL29662174 0.84 LPL (0.51) LPLLIPG
SCHEMBL18222125 0.84 LPL (0.51) LPLLIPG
SCHEMBL20114087 0.83 LPL (0.39) LPLLIPGROCK1IRAK4
SCHEMBL20114070 0.82 LPL (0.50) LPLLIPGROCK1IRAK4PRMT5
SCHEMBL3476592 0.82 HDAC6 (0.38) HIF1ALPLLIPGROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10886477-B2 Iridium complex and organic electroluminescence device using the same UDC IRELAND LIMITED (IE) 2021-01-05 US disclosed
US-20190296251-A1 IRIDIUM COMPLEX AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190296251-A1 IRIDIUM COMPLEX AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IMPA1, LAGE3, OCIAD1 HIF1A 4672/4885LPL 2650/4885LIPG 2700/4885
US-10886477-B2 Iridium complex and organic electroluminescence device using the same IMPA1, LAGE3, OCIAD1 HIF1A 4672/4885LPL 2650/4885LIPG 2700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.