SCHEMBL21392426

SCHEMBL21392426

CC(C)(C)c1ccc(N2c3ccccc3Oc3c(B4OC(C)(C)C(C)(C)O4)cccc32)cc1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 3/20 0.30
BTK Q06187 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21392268 0.79 HIF1A (0.37)
SCHEMBL14932219 0.78 P2RX4 (0.38)
SCHEMBL21381185 0.78 P2RX4 (0.33)
SCHEMBL19794967 0.77 JAK2 (0.37) JAK2BTK
SCHEMBL18222125 0.73 LPL (0.51)
SCHEMBL29662174 0.73 LPL (0.51)
SCHEMBL21895395 0.72 P2RX4 (0.32)
SCHEMBL31676557 0.72 P2RX4 (0.35) JAK2BTK
SCHEMBL21392464 0.72 ABL1 (0.37)
SCHEMBL24422387 0.72 P2RX4 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10886477-B2 Iridium complex and organic electroluminescence device using the same UDC IRELAND LIMITED (IE) 2021-01-05 US disclosed
US-20190296251-A1 IRIDIUM COMPLEX AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2019-09-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190296251-A1 IRIDIUM COMPLEX AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IMPA1, LAGE3, OCIAD1 JAK2 4751/4885BTK 1975/4885
US-10886477-B2 Iridium complex and organic electroluminescence device using the same IMPA1, LAGE3, OCIAD1 JAK2 4751/4885BTK 1975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.