Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | RAB9A | P51151 | 6/20 | 0.66 |
| ▸ | NPC1 | O15118 | 5/20 | 0.66 |
| ▸ | PAX8 | Q06710 | 4/20 | 0.66 |
| ▸ | GPX4 | P36969 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | JAK2 | O60674 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | FNIP1 | Q8TF40 | 1/20 | 0.50 |
| ▸ | FEM1B | Q9UK73 | 1/20 | 0.50 |
| ▸ | INSR | P06213 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21401721 | 0.88 | KMT2A (0.66) | KMT2AMEN1RAB9ANPC1PAX8 | |
| SCHEMBL21392985 | 0.87 | MEN1 (0.64) | KMT2AMEN1RAB9ANPC1PAX8 | |
| SCHEMBL21392964 | 0.85 | NPC1 (0.62) | KMT2AMEN1RAB9ANPC1PAX8 | |
| SCHEMBL21401863 | 0.85 | KMT2A (0.62) | KMT2AMEN1RAB9ANPC1PAX8 | |
| SCHEMBL21392987 | 0.84 | KMT2A (0.61) | KMT2AMEN1RAB9ANPC1PAX8 | |
| SCHEMBL21393049 | 0.84 | KMT2A (0.61) | KMT2AMEN1RAB9ANPC1PAX8 | |
| SCHEMBL21401880 | 0.84 | KMT2A (0.61) | KMT2AMEN1RAB9ANPC1PAX8 | |
| SCHEMBL21401891 | 0.81 | RAB9A (0.58) | KMT2AMEN1RAB9ANPC1PAX8 | |
| SCHEMBL21392821 | 0.80 | MEN1 (0.74) | KMT2AMEN1RAB9ANPC1PAX8 | |
| SCHEMBL15428399 | 0.80 | KMT2A (1.00) | KMT2AMEN1RAB9ANPC1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11666661-B2 | Methods and compounds for targeted autophagy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-06 | — | — | US | disclosed |
| US-11666661-B2 | Methods and compounds for targeted autophagy | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-06-06 | — | — | US | disclosed |
| WO-2019183600-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-09-26 | — | — | WO | disclosed |
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | FRONTIER MEDICINES CORPORATION | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190290778-A1 | METHODS AND COMPOUNDS FOR TARGETED AUTOPHAGY | ATG7, BECN1, SQSTM1 | KMT2A 3168/4885MEN1 4319/4885RAB9A 223/4885 |
| US-11666661-B2 | Methods and compounds for targeted autophagy | ATG7, BECN1, SQSTM1 | KMT2A 3168/4885MEN1 4319/4885RAB9A 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.