Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | POLA1 | P09884 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6365760 | 0.84 | KDM4E (0.51) | KDM4ETAS1R3TAS1R1POLA1MEN1 | |
| SCHEMBL4370992 | 0.81 | ADORA3 (0.46) | MEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL25968172 | 0.78 | KDM4E (0.52) | KDM4ETAS1R3TAS1R1POLA1MEN1 | |
| SCHEMBL24222098 | 0.77 | KDM4E (0.59) | KDM4ETAS1R3TAS1R1POLA1MEN1 | |
| SCHEMBL22883498 | 0.77 | KDM4E (0.59) | KDM4ETAS1R3TAS1R1POLA1MEN1 | |
| SCHEMBL28719205 | 0.77 | KDM4E (0.59) | KDM4ETAS1R3TAS1R1POLA1MEN1 | |
| SCHEMBL19146280 | 0.77 | KDM4E (0.59) | KDM4ETAS1R3TAS1R1POLA1MEN1 | |
| SCHEMBL20782390 | 0.76 | KDM4E (0.58) | KDM4ETAS1R3TAS1R1POLA1MEN1 | |
| SCHEMBL21637043 | 0.76 | KDM4E (0.58) | KDM4ETAS1R3TAS1R1POLA1MEN1 | |
| SCHEMBL21376544 | 0.76 | KDM4E (0.58) | KDM4ETAS1R3TAS1R1POLA1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4242212-A2 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | Takeda Pharmaceutical Company Limited (JP) | 2023-09-13 | — | — | EP | disclosed |
| WO-2019180683-A1 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-09-26 | — | — | WO | disclosed |