SCHEMBL4370992

SCHEMBL4370992

C[C@@]1(n2cnc3c(=O)[nH]c(N)nc32)O[C@H](CO)C[C@H]1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.46
TK1 P04183 2/20 0.43
BLM P54132 2/20 0.43
PNP P00491 2/20 0.43
USP2 O75604 1/20 0.43
TSHR P16473 1/20 0.43
EDNRA P25101 1/20 0.43
HTR2A P28223 1/20 0.43
RECQL P46063 1/20 0.43
HBB P68871 1/20 0.43
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
CYP3A4 P08684 1/20 0.41
NFKB1 P19838 1/20 0.41
VCP P55072 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL646779 0.88 ADORA3 (0.47) ADORA3TK1BLMPNPUSP2
SCHEMBL29490343 0.86 ADORA3 (0.46) ADORA3TK1BLMPNPUSP2
SCHEMBL30612742 0.82 ADORA3 (0.42) ADORA3TK1BLMPNPUSP2
SCHEMBL21392996 0.81 KDM4E (0.49) TSHRMEN1ALDH1A1KMT2A
SCHEMBL116166 0.81 ADORA3 (0.47) ADORA3TK1BLMPNPUSP2
SCHEMBL18537401 0.81 ADORA3 (0.47) ADORA3TK1BLMPNPUSP2
SCHEMBL16258667 0.81 ADORA3 (0.47) ADORA3TK1BLMPNPUSP2
SCHEMBL18537395 0.81 ADORA3 (0.47) ADORA3TK1BLMPNPUSP2
SCHEMBL13626438 0.81 ADORA3 (0.47) ADORA3TK1BLMPNPUSP2
SCHEMBL14620703 0.81 ADORA3 (0.47) ADORA3TK1BLMPNPUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2010659-A2 KITS AND METHODS FOR GENERATING 5' CAPPED RNA Epicentre Technologies (US) 2009-01-07 EP claimed
WO-2007120863-A2 KITS AND METHODS FOR GENERATING 5' CAPPED RNA EPICENTRE TECHNOLOGIES (US) 2007-10-25 WO claimed