Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115829 | 0.74 | PI4KA (0.32) | PDPK1PARP1CSNK2A2CSNK2A1KDM4E | |
| SCHEMBL22907637 | 0.74 | HPGD (0.38) | HPGD | |
| SCHEMBL129804 | 0.71 | PDPK1 (0.37) | PDPK1PARP1CSNK2A2CSNK2A1KDM4E | |
| SCHEMBL27285048 | 0.68 | PDPK1 (0.57) | PDPK1PARP1CSNK2A2CSNK2A1KDM4E | |
| SCHEMBL2139275 | 0.68 | PDPK1 (0.35) | PDPK1PARP1 | |
| Ammonia Solution, Strong SCHEMBL16871771 | 0.68 | PDPK1 (0.35) | PDPK1PARP1KDM4EALDH1A1HPGD | |
| SCHEMBL14438027 | 0.68 | PARP1 (0.34) | PDPK1PARP1MEN1KMT2A | |
| SCHEMBL2938699 | 0.67 | PDPK1 (0.37) | PDPK1KDM4EALDH1A1HPGD | |
| SCHEMBL4451632 | 0.67 | XDH (0.40) | PDPK1PARP1CSNK2A1KDM4EDYRK1A | |
| SCHEMBL1193368 | 0.67 | PDPK1 (0.34) | PDPK1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180683-A1 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-09-26 | — | — | WO | disclosed |