SCHEMBL129804

SCHEMBL129804

Cc1ncnc2[nH]cnc12

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 5/20 0.37
PI4KA P42356 2/20 0.33
PI4K2B Q8TCG2 2/20 0.33
PI4K2A Q9BTU6 2/20 0.33
PI4KB Q9UBF8 2/20 0.33
LRRK2 Q5S007 2/20 0.33
LMNA P02545 1/20 0.33
DRD3 P35462 1/20 0.33
XDH P47989 1/20 0.33
DRD1 P21728 1/20 0.33
PARP1 P09874 2/20 0.32
HRH2 P25021 1/20 0.32
HRH1 P35367 1/20 0.32
HRH4 Q9H3N8 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
TDP1 Q9NUW8 2/20 0.31
CSNK2A2 P19784 2/20 0.31
CSNK2A1 P68400 2/20 0.31
TP53 P04637 2/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Purine SCHEMBL731403 0.84
Adenine SCHEMBL3413247 0.74 PI4KA (0.48) PDPK1PI4KAPI4K2BPI4K2API4KB
SCHEMBL10285464 0.74 PI4KA (0.34) PI4KAPI4K2BPI4K2API4KBLRRK2
Adenine SCHEMBL3414603 0.74 PI4KA (0.48) PDPK1PI4KAPI4K2BPI4K2API4KB
Adenine SCHEMBL8110 0.74 PI4KA (0.48) PDPK1PI4KAPI4K2BPI4K2API4KB
Adenine SCHEMBL3416954 0.74 PI4KA (0.48) PDPK1PI4KAPI4K2BPI4K2API4KB
SCHEMBL8083818 0.74 MEN1 (0.33) PI4KAPI4K2BPI4K2API4KBLRRK2
SCHEMBL21913 0.74 YTHDC1 (0.47) PDPK1LRRK2LMNAXDHTP53
Adenine SCHEMBL1871837 0.74 PI4KA (0.44) PI4KAPI4K2BPI4K2API4KBLRRK2
SCHEMBL11491985 0.73 KDM4E (0.35) PI4KAPI4K2BPI4K2API4KBLRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1560 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4680730-A2 COMPOSITIONS AND METHODS FOR INTERNEURON MEDIATED DELIVERY OF CYTOTOXIC AGENTS TO THE BRAIN The Children's Hospital Of Philadelphia (US) 2026-01-21 EP claimed
EP-4602052-A1 PROTEIN-BASED SIGNAL AMPLIFICATION California Institute of Technology (US) 2025-08-20 EP claimed
WO-2025097124-A1 MOLECULAR SWITCH FOR INDUCIBLE GENE EXPRESSION THE BRIGHAM AND WOMEN’S HOSPITAL, INC. (US) 2025-05-08 WO claimed
WO-2025058093-A1 MODIFIED MITOCHONDRIA COMPRISING PRODRUG CONVERTING ENZYME AND USE THEREOF 주식회사 파이안바이오테크놀로지 2025-03-20 WO claimed
CN-112859550-B Aqueous phase developer for retarding aluminum corrosion and preparation method thereof 宁波南大光电材料有限公司 2024-11-29 CN claimed
WO-2024196794-A2 COMPOSITIONS AND METHODS FOR INTERNEURON MEDIATED DELIVERY OF CYTOTOXIC AGENTS TO THE BRAIN THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2024-09-26 WO claimed
US-20240285804-A1 ADENO-ASSOCIATED VIRAL (AAV) VECTORS FOR TISSUE-TARGETED EXPRESSION OF THERAPEUTIC GENES BRIGHAM & WOMENS HOSPITAL INC (US) 2024-08-29 US claimed
EP-4419692-A2 SYNTHETIC INTRONS FOR TARGETED GENE EXPRESSION Fred Hutchinson Cancer Center (US) 2024-08-28 EP claimed
EP-4388114-A1 CELL-TO-CELL DELIVERY OF RNA CIRCUITS California Institute of Technology (US) 2024-06-26 EP claimed
WO-2024124190-A1 ENGINEERED MICROORGANISMS FOR DELIVERY OF THERAPEUTIC AGENTS MICROBIAL MACHINES, INC. (US) 2024-06-13 WO claimed
US-5563049-A 2',3'-dideoxy purine nucleosides and process for the preparation thereof NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-10-08 US claimed
WO-1996028190-A1 NON-INVASIVE IMAGING OF GENE TRANSFER SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1996-09-19 WO claimed
EP-0540686-B1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1995-08-30 EP claimed
EP-0365556-B1 NUCLEOSIDE ANALOGUES GENENTECH INC (US) 1995-07-12 EP claimed
EP-0540686-A4 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1993-05-26 EP claimed
EP-0540686-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES. US COMMERCE (US) 1993-05-12 EP claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 WO claimed
EP-0399545-A2 Process for decontaminating cell cultures infested by mycoplasms BEHRINGWERKE Aktiengesellschaft (DE) 1990-11-28 EP claimed
EP-0098122-B1 PROCESSES FOR PRODUCING L-PROLINE BY FERMENTATION KYOWA HAKKO KOGYO CO., LTD. (JP) 1989-05-31 EP claimed
EP-0098122-A2 Processes for producing L-proline by fermentation KYOWA HAKKO KOGYO CO., LTD. (JP) 1984-01-11 EP claimed