Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ADCY5 | O95622 | 5/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21392994 | 0.78 | ADA (0.38) | ADACYP1A2CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL21393219 | 0.78 | ADCY5 (0.44) | CYP1A2CYP3A4ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL10475412 | 0.66 | AHCY (0.58) | ADCY5 | |
| SCHEMBL21392942 | 0.65 | ADCY5 (0.44) | ADACYP1A2CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL10475401 | 0.64 | AHCY (0.42) | ADCY5 | |
| SCHEMBL7474436 | 0.62 | ADA (0.42) | ADACYP1A2CYP3A4ALDH1A1CYP2C9 | |
| SCHEMBL25047848 | 0.61 | ADK (0.50) | ADCY5 | |
| SCHEMBL25049187 | 0.60 | PIP4K2A (0.39) | ADCY5 | |
| SCHEMBL19553770 | 0.60 | ADORA2A (0.49) | CYP1A2CYP3A4ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL21138474 | 0.59 | AHCY (0.48) | MAPK1ADCY5RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180683-A1 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-09-26 | — | — | WO | disclosed |