Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28310981 | 0.82 | POLB (0.64) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL15389250 | 0.81 | POLB (0.59) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28310319 | 0.77 | POLB (0.58) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL19961311 | 0.77 | POLB (0.46) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL19967733 | 0.77 | POLB (0.46) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10838180 | 0.76 | SRC (0.57) | SRCBTK | |
| SCHEMBL19889062 | 0.72 | BRD4 (0.52) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6618840 | 0.72 | LMNA (0.43) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29336549 | 0.72 | NPC1 (0.43) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21393225 | 0.72 | LMNA (0.54) | ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190293641-A1 | ASSAY | IMPERIAL COLLEGE INNOVATIONS, LTD. (GB) | 2019-09-26 | — | — | US | disclosed |