Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27603665 | 0.84 | CHRNB2 (0.62) | LMNACHRNB2CHRNA7CHRNA4KMT2A | |
| SCHEMBL10838180 | 0.83 | SRC (0.57) | PRMT5WDR77 | |
| SCHEMBL13024504 | 0.82 | CHRNB2 (0.63) | LMNACHRNB2CHRNA7CHRNA4KMT2A | |
| SCHEMBL1962198 | 0.82 | CHRNB2 (0.59) | LMNACHRNB2CHRNA7CHRNA4KMT2A | |
| SCHEMBL31430919 | 0.82 | CHRNB2 (0.59) | LMNACHRNB2CHRNA7CHRNA4KMT2A | |
| Oxalic Acid SCHEMBL1532842 | 0.81 | ALDH1A1 (0.59) | LMNACHRNB2CHRNA7CHRNA4KMT2A | |
| SCHEMBL5300891 | 0.79 | LMNA (0.67) | LMNACHRNB2CHRNA7CHRNA4KMT2A | |
| SCHEMBL18701778 | 0.79 | RIPK1 (0.65) | LMNACHRNB2CHRNA7CHRNA4KMT2A | |
| SCHEMBL21078063 | 0.79 | ALDH1A1 (0.64) | LMNACHRNB2CHRNA7CHRNA4KMT2A | |
| SCHEMBL38658031 | 0.78 | ALDH1A1 (0.59) | LMNACHRNB2CHRNA7CHRNA4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190293641-A1 | ASSAY | IMPERIAL COLLEGE INNOVATIONS, LTD. (GB) | 2019-09-26 | — | — | US | disclosed |