Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21393780 | 0.71 | CYP1A2 (0.33) | — | |
| SCHEMBL31368738 | 0.63 | MAPK1 (0.46) | ALDH1A1MAPK1SMN1; SMN2POLB | |
| SCHEMBL20187406 | 0.63 | KDM4E (0.47) | ALDH1A1MAPK1SMN1; SMN2POLB | |
| SCHEMBL22544354 | 0.63 | NPC1 (0.36) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5725168 | 0.63 | CSNK1A1 (0.38) | ALDH1A1MAPK1SMN1; SMN2POLB | |
| SCHEMBL21393825 | 0.62 | CSNK1A1 (0.33) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL31368709 | 0.62 | POLB (0.47) | ALDH1A1MAPK1SMN1; SMN2POLB | |
| SCHEMBL17692459 | 0.62 | SMN1; SMN2 (0.37) | ALDH1A1MAPK1SMN1; SMN2POLB | |
| SCHEMBL10872964 | 0.62 | POLB (0.33) | ALDH1A1MAPK1SMN1; SMN2POLB | |
| SCHEMBL1661890 | 0.62 | SMN1; SMN2 (0.40) | ALDH1A1MAPK1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019182925-A1 | OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2019-09-26 | — | — | WO | disclosed |