Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM5A | P29375 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.31 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21393711 | 0.74 | ALDH1A1 (0.39) | SMN1; SMN2LMNAALDH1A1KDM5AEPHX1 | |
| SCHEMBL21393743 | 0.74 | ALDH1A1 (0.32) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL12801473 | 0.69 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL23075986 | 0.69 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL13976334 | 0.65 | EPHX1 (0.34) | SMN1; SMN2LMNAALDH1A1EPHX1 | |
| SCHEMBL13976947 | 0.65 | EPHX1 (0.34) | SMN1; SMN2LMNAALDH1A1EPHX1 | |
| SCHEMBL13887704 | 0.65 | LMNA (0.56) | SMN1; SMN2LMNACYP1A2TDP1 | |
| SCHEMBL11472087 | 0.65 | ALDH1A1 (0.39) | SMN1; SMN2LMNAALDH1A1KDM5A | |
| SCHEMBL13827674 | 0.65 | — | — | |
| SCHEMBL25093254 | 0.64 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1CHRNB2CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078168-B2 | Substituted N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | Phenex Discovery Verwaltungs-GmbH (DE) | 2021-08-03 | — | — | US | disclosed |
| US-20190292160-A1 | SUBSTITUTED N-HYDROXYAMIDINOHETEROCYCLES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | Phenex Discovery Verwaltungs-GmbH (DE) | 2019-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078168-B2 | Substituted N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase | IDO1, IDO2, INMT | SMN1; SMN2 1421/4885LMNA 4632/4885ALDH1A1 650/4885 |
| US-20190292160-A1 | SUBSTITUTED N-HYDROXYAMIDINOHETEROCYCLES AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | IDO1, IDO2, INMT | SMN1; SMN2 1421/4885LMNA 4632/4885ALDH1A1 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.