Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394478 | 0.82 | TSHR (0.47) | RAB9ANPC1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL22479552 | 0.81 | MEN1 (0.52) | RAB9ANPC1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL21394862 | 0.80 | GCK (0.52) | RAB9ANPC1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL29356936 | 0.80 | NPC1 (0.46) | RAB9ANPC1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL29357283 | 0.80 | GCK (0.52) | RAB9ANPC1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL21394601 | 0.80 | NPC1 (0.46) | RAB9ANPC1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL21394784 | 0.74 | GCK (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL29356925 | 0.74 | GCK (0.44) | RAB9ANPC1ALDH1A1SMN1; SMN2PKM | |
| SCHEMBL21395077 | 0.74 | GCK (0.51) | MEN1KMT2APOLBKDM4EGRM5 | |
| SCHEMBL21394550 | 0.74 | KDM4E (0.51) | RAB9ANPC1ALDH1A1SMN1; SMN2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |