Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 9/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22479687 | 0.88 | CREBBP (0.51) | MEN1KMT2ACREBBPRAB9AALDH1A1 | |
| SCHEMBL21394512 | 0.82 | TSHR (0.53) | MEN1KMT2APOLBRAB9AALDH1A1 | |
| SCHEMBL21394479 | 0.81 | RAB9A (0.46) | MEN1KMT2APOLBCREBBPRAB9A | |
| SCHEMBL29356936 | 0.81 | NPC1 (0.46) | MEN1KMT2APOLBCREBBPRAB9A | |
| SCHEMBL21394601 | 0.81 | NPC1 (0.46) | MEN1KMT2APOLBCREBBPRAB9A | |
| SCHEMBL21394862 | 0.81 | GCK (0.52) | MEN1KMT2APOLBCREBBPRAB9A | |
| SCHEMBL29357283 | 0.81 | GCK (0.52) | MEN1KMT2APOLBCREBBPRAB9A | |
| SCHEMBL21394550 | 0.77 | KDM4E (0.51) | CREBBPRAB9AALDH1A1NPC1KDM4E | |
| SCHEMBL29353782 | 0.77 | KDM4E (0.51) | CREBBPRAB9AALDH1A1NPC1KDM4E | |
| SCHEMBL21394736 | 0.76 | NTRK1 (0.44) | MEN1KMT2APOLBCREBBPRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |