Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.50 |
| ▸ | VNN1 | O95497 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394488 | 0.91 | MEN1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL21394763 | 0.82 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL29355382 | 0.82 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL21394696 | 0.81 | RAB9A (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL21394854 | 0.79 | WNT3A (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL29359193 | 0.79 | WNT3A (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL21394921 | 0.79 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL21395080 | 0.78 | SMN1; SMN2 (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL21394724 | 0.78 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL21394847 | 0.78 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |