Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 3/20 | 0.46 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.44 |
| ▸ | DHX9 | Q08211 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 5/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.44 |
| ▸ | WNT1 | P04628 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394981 | 0.90 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1CSF1REP300DHX9 | |
| SCHEMBL21394827 | 0.88 | ALDH1A1 (0.50) | ALDH1A1CSF1REP300FSCN1DHX9 | |
| SCHEMBL29442864 | 0.88 | ALDH1A1 (0.50) | ALDH1A1CSF1REP300FSCN1DHX9 | |
| SCHEMBL21394681 | 0.86 | SMN1; SMN2 (0.48) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL29356936 | 0.84 | NPC1 (0.46) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL21394601 | 0.84 | NPC1 (0.46) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL21394615 | 0.83 | NPC1 (0.45) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL21394763 | 0.83 | NPC1 (0.51) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL29355382 | 0.83 | NPC1 (0.51) | SMN1; SMN2NPC1RAB9AALDH1A1PKM | |
| SCHEMBL21394646 | 0.82 | RAB9A (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |