Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 15/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356780 | 1.00 | NAMPT (0.48) | NAMPTCYP2C9HDAC1MAOBNPC1 | |
| SCHEMBL29358541 | 0.89 | NAMPT (0.52) | NAMPTCYP2C9HDAC1MAOBALDH1A1 | |
| SCHEMBL21394518 | 0.89 | NAMPT (0.52) | NAMPTCYP2C9HDAC1MAOBALDH1A1 | |
| SCHEMBL29357009 | 0.86 | MLLT1 (0.54) | NAMPTMAOBNPC1RAB9AALDH1A1 | |
| SCHEMBL21394492 | 0.86 | MLLT1 (0.54) | NAMPTMAOBNPC1RAB9AALDH1A1 | |
| SCHEMBL21394509 | 0.81 | RAB9A (0.43) | NPC1RAB9AALDH1A1PKMTSHR | |
| SCHEMBL29356750 | 0.81 | RAB9A (0.43) | NPC1RAB9AALDH1A1PKMTSHR | |
| SCHEMBL21394601 | 0.80 | NPC1 (0.46) | NPC1RAB9AALDH1A1PKMTSHR | |
| SCHEMBL29356936 | 0.80 | NPC1 (0.46) | NPC1RAB9AALDH1A1PKMTSHR | |
| SCHEMBL21394696 | 0.80 | RAB9A (0.52) | NAMPTNPC1RAB9AALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |