Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 10/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358541 | 1.00 | NAMPT (0.52) | NAMPTMAOBRETHDAC1S1PR3 | |
| SCHEMBL21394498 | 0.89 | NAMPT (0.48) | NAMPTMAOBHDAC1ALDH1A1CYP2C9 | |
| SCHEMBL29356780 | 0.89 | NAMPT (0.48) | NAMPTMAOBHDAC1ALDH1A1CYP2C9 | |
| SCHEMBL21394869 | 0.86 | MLLT1 (0.62) | NAMPTMAOBALDH1A1MLLT1F10 | |
| SCHEMBL29357058 | 0.86 | MLLT1 (0.62) | NAMPTMAOBALDH1A1MLLT1F10 | |
| SCHEMBL21394429 | 0.83 | RET (0.46) | NAMPTRETALDH1A1F10 | |
| SCHEMBL29356860 | 0.80 | ALDH1A1 (0.48) | ALDH1A1F10 | |
| SCHEMBL21394825 | 0.80 | ALDH1A1 (0.48) | ALDH1A1F10 | |
| SCHEMBL21394682 | 0.79 | ALDH1A1 (0.47) | ALDH1A1F10 | |
| SCHEMBL21394683 | 0.79 | ALDH1A1 (0.53) | ALDH1A1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |