Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22479552 | 0.82 | MEN1 (0.52) | TSHRRAB9ANPC1L3MBTL1MEN1 | |
| SCHEMBL29359147 | 0.81 | TSHR (0.47) | TSHRRAB9ANPC1L3MBTL1MEN1 | |
| SCHEMBL21394478 | 0.81 | TSHR (0.47) | TSHRRAB9ANPC1L3MBTL1MEN1 | |
| SCHEMBL29356991 | 0.81 | TSHR (0.47) | TSHRRAB9ANPC1L3MBTL1MEN1 | |
| SCHEMBL21394809 | 0.81 | TSHR (0.47) | TSHRRAB9ANPC1L3MBTL1MEN1 | |
| SCHEMBL21394641 | 0.81 | TSHR (0.47) | TSHRRAB9ANPC1L3MBTL1MEN1 | |
| SCHEMBL21394995 | 0.76 | NTRK1 (0.45) | TSHRRAB9ANPC1L3MBTL1MEN1 | |
| SCHEMBL21394993 | 0.76 | NTRK1 (0.43) | TSHRRAB9ANPC1L3MBTL1MEN1 | |
| SCHEMBL21395157 | 0.75 | CYP3A4 (0.47) | TSHRL3MBTL1 | |
| SCHEMBL21394572 | 0.75 | TSHR (0.44) | TSHRRAB9ANPC1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |