Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394518 | 0.83 | NAMPT (0.52) | RETNAMPTALDH1A1F10 | |
| SCHEMBL29358541 | 0.83 | NAMPT (0.52) | RETNAMPTALDH1A1F10 | |
| SCHEMBL21394867 | 0.82 | NPC1 (0.49) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29357020 | 0.82 | NPC1 (0.49) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21395174 | 0.80 | HCAR2 (0.46) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29354586 | 0.80 | L3MBTL1 (0.47) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21394760 | 0.80 | L3MBTL1 (0.47) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL29357084 | 0.80 | RAB9A (0.67) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21394817 | 0.80 | RAB9A (0.67) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21394767 | 0.80 | ALDH1A1 (0.47) | NPC1TSHRRAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |