Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29356856 | 0.88 | ALDH1A1 (0.47) | L3MBTL1RAB9ASMN1; SMN2NPC1TSHR | |
| SCHEMBL21394640 | 0.88 | ALDH1A1 (0.47) | L3MBTL1RAB9ASMN1; SMN2NPC1TSHR | |
| SCHEMBL29357041 | 0.87 | L3MBTL1 (0.46) | L3MBTL1GRM5RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21394626 | 0.87 | L3MBTL1 (0.46) | L3MBTL1GRM5RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21394598 | 0.86 | L3MBTL1 (0.56) | L3MBTL1RAB9ASMN1; SMN2NPC1TSHR | |
| SCHEMBL29354586 | 0.84 | L3MBTL1 (0.47) | L3MBTL1RAB9ASMN1; SMN2NPC1TSHR | |
| SCHEMBL21394587 | 0.84 | L3MBTL1 (0.47) | L3MBTL1RAB9ASMN1; SMN2NPC1TSHR | |
| SCHEMBL21394760 | 0.84 | L3MBTL1 (0.47) | L3MBTL1RAB9ASMN1; SMN2NPC1TSHR | |
| SCHEMBL21394762 | 0.84 | RAB9A (0.43) | L3MBTL1RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL21395122 | 0.84 | L3MBTL1 (0.43) | L3MBTL1RAB9ASMN1; SMN2NPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |