Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | GLS | O94925 | 11/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358393 | 0.86 | TSHR (0.53) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL21394637 | 0.86 | TSHR (0.53) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL21394627 | 0.83 | GLS (0.44) | GLSHIF1AEPAS1 | |
| SCHEMBL21394572 | 0.79 | TSHR (0.44) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL29357109 | 0.79 | TSHR (0.44) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL21394598 | 0.79 | L3MBTL1 (0.56) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL21394634 | 0.79 | TSHR (0.43) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL29355468 | 0.79 | L3MBTL1 (0.46) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL21394578 | 0.79 | L3MBTL1 (0.46) | TSHRKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL21384513 | 0.78 | RAB9A (0.42) | GLSHIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |