Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394506 | 0.90 | RAB9A (0.49) | F10RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL21395178 | 0.89 | CYP11B1 (0.51) | F10RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL21394825 | 0.88 | ALDH1A1 (0.48) | F10RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL29356860 | 0.88 | ALDH1A1 (0.48) | F10RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL21394976 | 0.88 | KDM4E (0.41) | F10CREBBPCYP1A2MAPTDEGS1 | |
| SCHEMBL21394761 | 0.85 | MAOB (0.42) | F10RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL29357123 | 0.85 | MAOB (0.42) | F10RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL21394762 | 0.85 | RAB9A (0.43) | F10RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL21394648 | 0.84 | SIRT2 (0.43) | F10RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL21394480 | 0.84 | MAPT (0.44) | F10RAB9ASMN1; SMN2TP53NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |