Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 2/20 | 0.42 |
| ▸ | GCK | P35557 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21395121 | 0.91 | SMN1; SMN2 (0.46) | DEGS1ALDH1A1KCNQ3KCNQ2MAOB | |
| SCHEMBL21394642 | 0.88 | GCK (0.48) | DEGS1GCKKDM4EALDH1A1CXCR2 | |
| SCHEMBL21394946 | 0.88 | GRM5 (0.47) | GCKKDM4EALDH1A1CXCR2HDAC3 | |
| SCHEMBL21394651 | 0.85 | ALDH1A1 (0.49) | GCKALDH1A1F10 | |
| SCHEMBL21394657 | 0.85 | ALDH1A1 (0.49) | GCKALDH1A1F10 | |
| SCHEMBL21394929 | 0.85 | NPC1 (0.39) | DEGS1KDM4EALDH1A1F10S1PR1 | |
| SCHEMBL21395182 | 0.84 | GSK3B (0.44) | DEGS1KDM4EALDH1A1CXCR2KCNQ3 | |
| SCHEMBL21394717 | 0.83 | CACNA1H (0.39) | DEGS1KDM4EALDH1A1KCNQ3KCNQ2 | |
| SCHEMBL21394699 | 0.82 | FFAR2 (0.42) | DEGS1ALDH1A1F10 | |
| SCHEMBL21394997 | 0.81 | KCNQ3 (0.57) | DEGS1GCKKDM4EALDH1A1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |