Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394703 | 0.87 | ALDH1A1 (0.43) | ALDH1A1MAPTLMNAHIF1ASNCA | |
| SCHEMBL21394699 | 0.86 | FFAR2 (0.42) | ALDH1A1PYGLF10DEGS1NPC1 | |
| SCHEMBL29358525 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAHIF1ASNCA | |
| SCHEMBL21394767 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAHIF1ASNCA | |
| SCHEMBL21394728 | 0.84 | ALDH1A1 (0.49) | ALDH1A1LMNAF10MEN1KMT2A | |
| SCHEMBL21394657 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTF10MEN1KMT2A | |
| SCHEMBL21394651 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTF10MEN1KMT2A | |
| SCHEMBL21395090 | 0.83 | ALDH1A1 (0.51) | ALDH1A1LMNAF10MEN1KMT2A | |
| SCHEMBL21394644 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAHIF1ASNCA | |
| SCHEMBL22479547 | 0.82 | ALDH1A1 (0.50) | ALDH1A1LMNAF10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |