Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442848 | 0.89 | SNCA (0.45) | SNCAFSCN1HDAC3HDAC1HDAC2 | |
| SCHEMBL21394730 | 0.89 | SNCA (0.45) | SNCAFSCN1HDAC3HDAC1HDAC2 | |
| SCHEMBL21384407 | 0.78 | L3MBTL1 (0.43) | LMNAMAPTSNCAHIF1AKMT2A | |
| SCHEMBL29357022 | 0.78 | ALDH1A1 (0.44) | LMNAMAPTFLT1KDRSNCA | |
| SCHEMBL29356947 | 0.78 | L3MBTL1 (0.43) | LMNAMAPTSNCAHIF1AKMT2A | |
| SCHEMBL21394811 | 0.78 | ALDH1A1 (0.44) | LMNAMAPTFLT1KDRSNCA | |
| SCHEMBL29354586 | 0.76 | L3MBTL1 (0.47) | LMNAMAPTSNCAKMT2AMEN1 | |
| SCHEMBL21394760 | 0.76 | L3MBTL1 (0.47) | LMNAMAPTSNCAKMT2AMEN1 | |
| SCHEMBL21384473 | 0.75 | LMNA (0.41) | LMNAMAPTSNCAHIF1AKMT2A | |
| SCHEMBL29358562 | 0.75 | LMNA (0.41) | LMNAMAPTSNCAHIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |