Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394678 | 0.89 | NPC1 (0.49) | NR3C2KDM5AKDM4CKDM5BSNCA | |
| SCHEMBL21394844 | 0.82 | SNCA (0.47) | NR3C2SNCANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29442866 | 0.82 | SNCA (0.47) | NR3C2SNCANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21395148 | 0.79 | RAB9A (0.45) | NR3C2KDM5AKDM4CKDM5BSNCA | |
| SCHEMBL29442811 | 0.79 | SNCA (0.48) | NR3C2SNCANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21394469 | 0.79 | SNCA (0.48) | NR3C2SNCANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29358085 | 0.78 | NPC1 (0.48) | SNCANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21394658 | 0.78 | NPC1 (0.48) | SNCANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21394865 | 0.77 | NR3C2 (0.47) | NR3C2SNCANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29358065 | 0.77 | NR3C2 (0.47) | NR3C2SNCANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |