Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394469 | 1.00 | SNCA (0.48) | SNCARETTP53POLBSMN1; SMN2 | |
| SCHEMBL29358598 | 0.93 | NPC1 (0.46) | SNCARETTP53POLBSMN1; SMN2 | |
| SCHEMBL21394754 | 0.93 | NPC1 (0.46) | SNCARETTP53POLBSMN1; SMN2 | |
| SCHEMBL21394764 | 0.85 | NPC1 (0.50) | SNCARETSMN1; SMN2NPC1RAB9A | |
| SCHEMBL21395076 | 0.82 | GRM5 (0.44) | NPC1RAB9AGRM5WNT3A | |
| SCHEMBL29442866 | 0.82 | SNCA (0.47) | SNCARETTP53SMN1; SMN2NPC1 | |
| SCHEMBL21394844 | 0.82 | SNCA (0.47) | SNCARETTP53SMN1; SMN2NPC1 | |
| SCHEMBL21395171 | 0.81 | NPC1 (0.47) | SNCARETTP53SMN1; SMN2NPC1 | |
| SCHEMBL21394920 | 0.80 | ALDH1A1 (0.49) | SNCANPC1RAB9AALDH1A1 | |
| SCHEMBL21384504 | 0.80 | SNCA (0.48) | SNCARETSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |