Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GCK | P35557 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394948 | 0.85 | MEN1 (0.54) | RXFP1CREBBPMEN1KMT2AGCK | |
| SCHEMBL29358548 | 0.85 | MEN1 (0.54) | RXFP1CREBBPMEN1KMT2AGCK | |
| SCHEMBL21394510 | 0.83 | ALDH1A1 (0.48) | RXFP1CREBBPLMNAMEN1KMT2A | |
| SCHEMBL29358244 | 0.83 | ALDH1A1 (0.48) | RXFP1CREBBPLMNAMEN1KMT2A | |
| SCHEMBL21394759 | 0.80 | MEN1 (0.53) | CREBBPMEN1KMT2AGCKNPC1 | |
| SCHEMBL29354520 | 0.80 | MEN1 (0.53) | CREBBPMEN1KMT2AGCKNPC1 | |
| SCHEMBL21395089 | 0.79 | MEN1 (0.52) | CREBBPLMNAPOLBMEN1KMT2A | |
| SCHEMBL29353929 | 0.79 | RAB9A (0.43) | RXFP1LMNAPOLBMEN1KMT2A | |
| SCHEMBL21394436 | 0.79 | RAB9A (0.43) | RXFP1LMNAPOLBMEN1KMT2A | |
| SCHEMBL22479585 | 0.74 | MEN1 (0.52) | LMNAMEN1KMT2AGCKRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |