Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 3/20 | 0.44 |
| ▸ | EP300 | Q09472 | 3/20 | 0.44 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.44 |
| ▸ | DHX9 | Q08211 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 4/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.44 |
| ▸ | WNT1 | P04628 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442864 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPK1MEN1KMT2ACSF1R | |
| SCHEMBL21395080 | 0.88 | SMN1; SMN2 (0.50) | ALDH1A1MEN1KMT2ACSF1REP300 | |
| SCHEMBL21395017 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AF10 | |
| SCHEMBL21394681 | 0.86 | SMN1; SMN2 (0.48) | ALDH1A1CSF1RF10EP300GSK3B | |
| SCHEMBL29356860 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AF10 | |
| SCHEMBL21394825 | 0.84 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AF10 | |
| SCHEMBL29357020 | 0.82 | NPC1 (0.49) | ALDH1A1MEN1KMT2AF10GSK3B | |
| SCHEMBL21394867 | 0.82 | NPC1 (0.49) | ALDH1A1MEN1KMT2AF10GSK3B | |
| SCHEMBL21394981 | 0.82 | SMN1; SMN2 (0.53) | ALDH1A1CSF1REP300DHX9GSK3B | |
| SCHEMBL21394476 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118084800-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084801-A | Compounds and uses thereof | 詹森药业有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-112312913-B | Compounds and uses thereof | 詹森药业有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-114174273-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-112312913-A | Compounds and uses thereof | 优曼尼蒂治疗公司 | 2021-02-02 | — | — | CN | disclosed |
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |