Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPRF | P10586 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12890137 | 0.84 | LMNA (0.48) | LMNAKDM4EGAAALDH1A1MAPT | |
| SCHEMBL1857270 | 0.80 | PTGS2 (0.50) | LMNAKDM4EGAAALDH1A1MAPT | |
| SCHEMBL14966301 | 0.78 | KDM4E (0.43) | LMNAKDM4EGAASTAT3ALDH1A1 | |
| SCHEMBL9340989 | 0.77 | TSHR (0.45) | LMNAKDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL1503865 | 0.77 | MAPK1 (0.51) | LMNAKDM4EGAAALDH1A1MAPT | |
| SCHEMBL4428207 | 0.75 | OPRD1 (0.51) | LMNAKDM4EGAAALDH1A1MAPT | |
| SCHEMBL1255539 | 0.74 | LMNA (0.62) | LMNAKDM4EGAAALDH1A1MAPT | |
| SCHEMBL22861795 | 0.74 | CA12 (0.49) | LMNAKDM4EGAAALDH1A1MAPT | |
| SCHEMBL25422243 | 0.74 | LMNA (0.58) | LMNAKDM4EGAAALDH1A1SLC6A2 | |
| SCHEMBL15024022 | 0.73 | LMNA (0.57) | LMNAKDM4EGAAALDH1A1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |