Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.46 |
| ▸ | GCK | P35557 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394642 | 0.91 | GCK (0.48) | RAB9AALDH1A1CXCR2GCKCXCR1 | |
| SCHEMBL21394651 | 0.88 | ALDH1A1 (0.49) | RAB9AALDH1A1NPC1SMN1; SMN2PKM | |
| SCHEMBL21394657 | 0.88 | ALDH1A1 (0.49) | RAB9AALDH1A1NPC1SMN1; SMN2PKM | |
| SCHEMBL21394645 | 0.88 | DEGS1 (0.42) | ALDH1A1CXCR2GCKKDM4EHDAC3 | |
| SCHEMBL21395121 | 0.85 | SMN1; SMN2 (0.46) | RAB9AALDH1A1NPC1SMN1; SMN2PKM | |
| SCHEMBL29355382 | 0.84 | NPC1 (0.51) | RAB9AALDH1A1NPC1SMN1; SMN2PKM | |
| SCHEMBL21394763 | 0.84 | NPC1 (0.51) | RAB9AALDH1A1NPC1SMN1; SMN2PKM | |
| SCHEMBL21394624 | 0.83 | NPC1 (0.48) | RAB9AALDH1A1NPC1SMN1; SMN2PKM | |
| SCHEMBL29358776 | 0.83 | NPC1 (0.48) | RAB9AALDH1A1NPC1SMN1; SMN2PKM | |
| SCHEMBL21394854 | 0.81 | WNT3A (0.52) | RAB9AALDH1A1NPC1SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |