Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.60 |
| ▸ | PPARG | P37231 | 13/20 | 0.60 |
| ▸ | PPARD | Q03181 | 4/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811237 | 1.00 | PPARA (0.60) | PPARAPPARGPPARDTAAR1FFAR1 | |
| SCHEMBL10909366 | 0.83 | PPARG (0.54) | PPARAPPARGTAAR1 | |
| SCHEMBL6055973 | 0.82 | PPARA (0.73) | PPARAPPARGPPARD | |
| SCHEMBL4455247 | 0.82 | PPARA (0.73) | PPARAPPARGPPARD | |
| SCHEMBL1670312 | 0.81 | PPARA (0.69) | PPARAPPARGPPARD | |
| SCHEMBL4993002 | 0.81 | PPARA (0.69) | PPARAPPARGPPARD | |
| SCHEMBL756254 | 0.81 | PPARG (0.57) | PPARAPPARGPPARD | |
| SCHEMBL7617610 | 0.81 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL6311891 | 0.80 | TAAR1 (0.64) | TAAR1FFAR1 | |
| SCHEMBL14332309 | 0.80 | PPARA (0.58) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906669-B2 | Metallocene-based phosphorus chiral phosphines | SOLVIAS AG (CH) | 2011-03-15 | — | — | US | disclosed |
| EP-1844061-B1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | SOLVIAS AG (CH) | 2010-08-04 | — | — | EP | disclosed |
| US-20090137824-A1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | PHOENIX CHEMICALS LTD (GB) | 2009-05-28 | — | — | US | disclosed |
| US-20080242876-A1 | Process For the Manufacture of Substituted Propionic Acids | PHOENIX CHEMICALS LTD. (GB) | 2008-10-02 | — | — | US | disclosed |
| EP-1844061-A1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | Phoenix Chemicals Limited (GB) | 2007-10-17 | — | — | EP | disclosed |
| EP-1838654-A1 | PROCESS FOR THE MANUFACTURE OF SUBSTITUTED PROPIONIC ACIDS | Phoenix Chemicals Limited (GB) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006075166-A1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | PHOENIX CHEMICALS LTD. (GB) | 2006-07-20 | — | — | WO | disclosed |
| WO-2006075177-A1 | PROCESS FOR THE MANUFACTURE OF SUBSTITUTED PROPIONIC ACIDS | PHOENIX CHEMICALS LTD. (GB) | 2006-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137824-A1 | METALLOCENE-BASED PHOSPHORUS CHIRAL PHOSPHINES | POLL, ZNF207, ZC3HAV1L | PPARA 164/4885PPARG 443/4885PPARD 505/4885 |
| US-20080242876-A1 | Process For the Manufacture of Substituted Propionic Acids | AS3MT, PPA1, AGPS | PPARA 97/4885PPARG 521/4885PPARD 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.