Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.54 |
| ▸ | PPARA | Q07869 | 4/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953540 | 0.85 | PPARA (0.50) | PPARGPPARATAAR1CYP1A2CTBP2 | |
| SCHEMBL811237 | 0.83 | PPARA (0.60) | PPARGPPARATAAR1 | |
| SCHEMBL2139497 | 0.83 | PPARA (0.60) | PPARGPPARATAAR1 | |
| SCHEMBL48107 | 0.82 | TAAR1 (0.55) | TAAR1CYP1A2CTBP2MEN1KMT2A | |
| SCHEMBL1486323 | 0.81 | SRR (0.62) | PPARGPPARAACE | |
| SCHEMBL1486321 | 0.81 | SRR (0.62) | PPARGPPARAACE | |
| SCHEMBL2626716 | 0.81 | SRR (0.62) | PPARGPPARAACE | |
| SCHEMBL28748038 | 0.81 | SRR (0.47) | PPARGPPARAACE | |
| SCHEMBL146611 | 0.81 | TAAR1 (0.66) | TAAR1CYP1A2 | |
| SCHEMBL4596077 | 0.81 | TAAR1 (0.66) | TAAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596828-A | Topical | MERCK & CO., INC. (US) | 1986-06-24 | — | — | US | disclosed |