Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 11/20 | 0.58 |
| ▸ | ITK | Q08881 | 1/20 | 0.58 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | SCD | O00767 | 12/20 | 0.53 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353742 | 1.00 | SCD5 (0.58) | SCD5ITKNAMPTSCDFSCN1 | |
| SCHEMBL21394917 | 0.80 | TSHR (0.54) | MEN1LMNAMAPTKMT2ATSHR | |
| SCHEMBL29353982 | 0.80 | TSHR (0.54) | MEN1LMNAMAPTKMT2ATSHR | |
| SCHEMBL21394622 | 0.80 | TSHR (0.51) | MEN1LMNAMAPTKMT2ATSHR | |
| SCHEMBL21394489 | 0.79 | TSHR (0.50) | FSCN1MEN1LMNAMAPTKMT2A | |
| SCHEMBL21394957 | 0.78 | ITK (0.58) | SCD5ITKNAMPTSCDFSCN1 | |
| SCHEMBL22557197 | 0.77 | ITK (0.64) | SCD5ITKNAMPTSCDMEN1 | |
| SCHEMBL21394760 | 0.75 | L3MBTL1 (0.47) | MEN1LMNAMAPTKMT2ATSHR | |
| SCHEMBL29354586 | 0.75 | L3MBTL1 (0.47) | MEN1LMNAMAPTKMT2ATSHR | |
| SCHEMBL22479698 | 0.74 | ITK (0.54) | SCD5ITKNAMPTSCDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |