Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.43 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.43 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.43 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21394917 | 0.86 | TSHR (0.54) | TSHRMEN1KMT2ATDP1KDM4E | |
| SCHEMBL29353982 | 0.86 | TSHR (0.54) | TSHRMEN1KMT2ATDP1KDM4E | |
| SCHEMBL21394489 | 0.84 | TSHR (0.50) | TSHRMEN1KMT2ATDP1KDM4E | |
| SCHEMBL21394760 | 0.82 | L3MBTL1 (0.47) | TSHRMEN1KMT2ATDP1KDM4E | |
| SCHEMBL29354586 | 0.82 | L3MBTL1 (0.47) | TSHRMEN1KMT2ATDP1KDM4E | |
| SCHEMBL21394804 | 0.81 | LMNA (0.66) | MEN1KMT2AKDM4EL3MBTL1HTT | |
| SCHEMBL29353742 | 0.80 | SCD5 (0.58) | TSHRMEN1KMT2AMAPTLMNA | |
| SCHEMBL21394983 | 0.80 | SCD5 (0.58) | TSHRMEN1KMT2AMAPTLMNA | |
| SCHEMBL21384407 | 0.79 | L3MBTL1 (0.43) | TSHRMEN1KMT2ATDP1KDM4E | |
| SCHEMBL29356947 | 0.79 | L3MBTL1 (0.43) | TSHRMEN1KMT2ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198026-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2020-10-01 | — | — | WO | disclosed |
| WO-2019183587-A1 | COMPOUNDS AND USES THEREOF | YUMANITY THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |